Description
Uperio is a cardiovascular drug used in the treatment of symptomatic heart failure in patients with systolic dysfunction. At the same time, the drug Uperio has been shown to reduce hospitalization and mortality from cardiovascular disease.
So what is the use of Uperio?
1. What is the drug Uperio?
Uperio drug belongs to the group of cardiovascular drugs, which are prepared with many strengths and ingredients including:
Uperio 50mg Each tablet contains 24.3 mg sacubitril. 25.7 mg valsartan Uperio 100mg each tablet contains 48.6mg sacubitril and 51.4mg valsartan Uperio 200mg each tablet contains 97.2mg sacubitril and 102.8mg valsartan
2. Indications and contraindications
2.1 Indications for use of the drug Uperio
Uperio is indicated for use in the treatment of symptomatic heart failure in patients with systolic dysfunction. Uperio has been shown to reduce hospital admissions for heart failure and cardiovascular mortality compared with enalapril. In addition, Uperio has also been shown to reduce mortality from many other causes compared with enalapril.
Besides the above uses, Uperio can also be used to treat a number of other conditions that are not listed above. Therefore, before taking the drug, consult your doctor for advice and effective use of the drug.
2.2 Contraindication to the use of the drug Uperio Contraindicated to use the drug Uperio to treat the following cases:
Hypersensitivity to the components of the drug Pregnant women History of angioedema related to receptor blockers angiotensin Severe liver failure Biliary cirrhosis Cholestasis
3. Usage and dosage of the drug Upio
The drug Uperio is made in the form of tablets, so it can be taken on an empty stomach or on an empty stomach. Patients should take the medicine with a full glass of water to avoid stomach irritation. Dosage of Uperio will depend on the condition and age of the patient such as:
The recommended starting dose is 100mg/day for patients who are not taking angiotensin-converting enzyme inhibitors or blockers. angiotensin II receptor, and is also considered for patients who have previously used these agents. Patients with systolic blood pressure ≥100-110 mmHg/ not taking ACEIs or angiotensin II receptor blockers/ previously taking these drugs at low doses: use/recommendation/consider initiation of 50 mg twice /day. Double dose every 2 to 4 weeks to target dose of 200 mg twice daily as tolerated. If systolic blood pressure ≤ 95 mmHg, symptomatic hypotension, clinically significant hyperkalemia, renal dysfunction: adjust dose of concomitant drugs, temporarily reduce dose/discontinue Uperio. Elderly patients: dose should be suitable for renal function, moderate or severe renal impairment, moderate hepatic impairment: starting dose is 50 mg twice daily, end-stage renal disease: not recommended. Children and adolescents < 18 years: Safety and efficacy have not been established. Use Uperio regularly to get the most benefit from it. To use it safely, take Uperio exactly as directed by your doctor, do not use it more often, smaller or longer than prescribed. Absolutely do not abuse the drug for too long for a long time or arbitrarily increase the dose of the drug. Because this not only makes the condition worse, but also increases the risk of unwanted effects.
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