Dolutegravir/Lamiduvine/Tenofovir Disoproxil Fumarate (50/300/300)mg

Description

Dolutegravir/Lamiduvine/Tenofovir Disoproxil Fumarate (50/300/300)mg belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is a combination of three drugs, namely: Dolutegravir (integrase inhibitor), Lamivudine (nucleoside reverse transcriptase inhibitor), and Tenofovir disoproxil fumarate (nucleotide reverse transcriptase inhibitor). Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE helps in treating HIV infection.

Take DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE as prescribed. Swallow DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE as a whole with water; do not chew or crush the tablet. You are advised to take DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, diarrhoea, headache, pain, rash, depression, fever, cough, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Practise safe sex and other necessary precautions as DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE. DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may cause dizziness, so drive with caution. DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is not recommended for children weighing below 35kgs. Keep your doctor informed about your health condition and medicines you are taking to prevent any side effects/interactions.

Use

HIV infection

Medicinal Benefits

DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is a combination of three drugs, namely: Dolutegravir, Lamivudine and Tenofovir disoproxil fumarate. DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. Dolutegravir is an integrase inhibitor that increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. They work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE helps in treating HIV infection.

Directions for Use

Take DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE with or without food. Swallow DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE as a whole with water; do not chew or crush the tablet. Depending on your medical condition, your doctor will decide for how long you need to take DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE.

Storage

Store in a cool and dry place away from sunlight

Side Effects

Fatigue
Diarrhoea
Headache
Pain
Rash
Depression
Fever
Cough
Insomnia

In-Depth Precautions and Warning

Drug Warnings

Do not take DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE if you are allergic to any of its contents. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney or liver problems, if you are taking dofetilide. Practise safe sex and other necessary precautions as DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE. DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may cause dizziness, so drive with caution. DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is not recommended for children weighing below 35kgs. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Drug-Drug Interactions: DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may have interaction with an anti-arrhythmic agent (dofetilide)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: DOLUTEGRAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may have interactions with hepatitis B, pancreatitis, bone problems, kidney or liver problems.